Journey to Florence to discover how Leonardo da Vinci used science, from human dissections to innovative painting techniques, to create his legendary artwork. Learn why Mona Lisa's smile is so captivating—and what it took to create it. WGBH Contributor Sue O’Connell sits down with producer and director of Decoding da Vinci, Doug Hamilton, Dr. Trudy Van Houten of Boston University's School of Medicine and Dr. Lorenzo Buonanno of UMass Boston to explore the science behind da Vinci's masterpieces.