Particles of Thought

Nature has been solving problems for billions of years. Evolutionary biologist Sean B. Carroll reveals why scientists still turn to evolution’s inventions for life-saving breakthroughs, from GLP-1 drugs to statins.For more, check out the extended interview with Sean B. Carroll.Learn more about NOVA and subscribe to our YouTube channel.

In 2024, scientists claimed they achieved the unthinkable: the birth of dire wolf pups, reviving a species that vanished thousands of years ago. Now, those pups are growing—and changing. Evolutionary biologist Beth Shapiro reveals what it’s like to watch these predators mature into modern beasts.For more, check out the extended interview with Beth Shapiro. Learn more about NOVA and subscribe to our YouTube channel.

Is AI coming for your job? AI Expert Hany Farid breaks down how AI is taking jobs once considered “future-proof” and shares his advice to prepare young people for the future.For more, check out the extended interview with Hany Farid. Learn more about NOVA and subscribe to our YouTube channel.

What does it feel like to make one of the biggest discoveries in physics? Adam Riess knows — because his work revealed that the universe isn’t just expanding, it’s accelerating. In this episode, the Nobel Prize–winning astrophysicist takes us behind the scenes of the moment that changed cosmology forever. How did his team use exploding stars as “standard candles” to measure the cosmos? Why did the data point to a mysterious force now called dark energy, making up nearly 70% of the universe? And what’s behind today’s biggest cosmic puzzle: the Hubble tension? Plus, Adam shares what new telescopes could uncover — and why the next decade might rewrite the laws of physics all over again. Learn more about NOVA and subscribe to our YouTube channel. —————————Guest Bio: Adam Riess is an astrophysicist, professor at Johns Hopkins University, and a distinguished astronomer at Space Telescope Science Institute. In 2011, he was named as a co-winner of the Nobel Prize in Physics for his contributions to the discovery that the expansion rate of the universe is accelerating. Since then, he has continued refining measurements of cosmic expansion and the Hubble constant, aiming to find and measure the most distant type Ia supernovae known, to probe the origin of cosmic acceleration.Timestamps(00:00:00) Introduction(00:03:16) What Is a Type Ia Supernova? (00:10:52) The Discovery of Dark Energy(00:44:39) What Is the Hubble Tension?(00:58:59) Winning a Nobel Prize(01:15:32) Credits

The universe isn’t adding up—and it’s creating a crisis in cosmology. Nobel Prize winner Adam Riess explains why measurements of the universe’s expansion rate from its earliest light and from nearby galaxies don’t match, and how this growing gap threatens the foundations of our standard model of the cosmos.Learn more about NOVA and subscribe to our YouTube channel.

Discovering dark energy wasn’t just thrilling—it was terrifying. Nobel Prize Winner Adam Riess explains the nerve-wracking process behind confirming that the universe’s expansion is accelerating and why Einstein’s so-called “biggest blunder” turned out to be anything but.Learn more about NOVA and subscribe to our YouTube channel.

Fame can hijack the brain like a drug—activating the same reward circuits that fuel a relentless chase for dopamine highs. Neuroscientist Heather Berlin reveals the antidote—and why even social media fame can trigger this cycle.For more, check out the extended interview with Heather Berlin.Learn more about NOVA and subscribe to our YouTube channel.

Fossilization isn’t luck - it’s geology. Paleobotanist Kirk Johnson explains how fossils only form in certain conditions, the tricks to finding them, and why one fossil leaf can lead to thousands more. For more, check out the extended interview with Kirk Johnson.Learn more about NOVA and subscribe to our YouTube channel.

Speech is rare in the animal kingdom because it requires a very specific brain architecture. Neuroscientist Erich Jarvis explains how duplicating neural pathways for movement unlocked language, dancing, and even advanced problem-solving in more than just humans.For more, check out the extended interview with Erich Jarvis. Learn more about NOVA and subscribe to our YouTube channel.

How does evolution invent entirely new things, like limbs, wings, and venom? Evolutionary biologist Sean B. Carroll joins us to reveal the hidden rules behind nature’s creativity and the genetic toolkit that makes it possible. Carroll explains how the same set of genes can build wildly different creatures — from fruit flies to lobsters — simply by rewiring their genetic circuits. Discover why developmental biology holds the key to understanding evolution, how snake venom evolved, and why medicines like GLP-1 drugs and statins trace their origins to nature’s own innovations. Plus, what the emergence of new species tells us about life’s future and the surprising power of evolution to repurpose old parts in new ways. Learn more about NOVA and subscribe to our YouTube channel. —————————Guest Bio: Sean B. Carroll is a renowned evolutionary biologist and author whose work has inspired a deeper public understanding of evolution and the natural world. He is an Investigator at Howard Hughes Medical Institute (HHMI), where he was formerly Head of HHMI Tangled Bank Studios, and led the Department of Science Education from 2010-2023. He is also a Professor of Biology at the University of Maryland. His research focuses on genes that influence the evolution of animal diversity.