U.S. Rep. Mike Capuano (D-Somerville) will not run for John Kerry’s U.S. Senate seat.

“After careful consideration, I have decided not to enter the race for U.S. Senate,” Capuano said in a statement. “Instead, I look forward to focusing on the important issues facing the new Congress. My current work in the House and whatever opportunities the future may hold, afford me the greatest honor of my life, fighting for the citizens of the commonwealth.”

Capuano ran for the Senate seat vacated by the late Sen. Ted Kennedy in a 2010 special election, losing to Attorney General Martha Coakley. His decision leaves the race to replace Kerry, should he be confirmed as U.S. Secretary of State, a field of one: U.S. Rep. Ed Markey (D-Malden).

Last week, State Rep. Ben Downing announced he would not run. Rep, Stephen Lynch (D-South Boston) and former Republican Sen. Scott Brown have been widely reported as considering a run