It’s the most successful athletic fundraising event in the country, and this weekend, for the 39th consecutive year, thousands of Pan-Mass Challenge riders will hit the road to raise money for life-saving cancer research. Last year, more than 6,000 cyclists raised a record $51 million, every penny of which was donated to the Dana-Farber Cancer Institute. Since the race first began, it’s raised a total of $598 million — and this year they’re set to pass the $600 million mark.

Jim Braude was joined by WBZ-TV News Anchor Lisa Hughes, who is riding in the PMC again this year, and the man who started it all in 1980, Pan-Mass Challenge Founder and Executive Director Billy Starr.