• Boston Globe editor Brian McGrory discussed the murders of journalists James Foley and Steven Sotloff, and the difficult decision editors have in dispatching journalists to cover dangerous areas. McGrory also talked about the launch of the Globe site Crux, and his paper's primary endorsements. (Starts at 1:00)
  • Medical ethicist Art Caplan was back to talk about a long list of topics: the NIH starting clinical trials on the Ebola virus; how electrically "zapping" the brain can improve memory; and the unexpectedly high cost of generic drugs. (Starts at 26:00)
  • Wednesday's Open Mic guest was Juliette Kayyem. Kayyem is a former Homeland Security administrator and candidate for governor. Kayyem talked about the ISIS threat, a lack of diversity within the Boston Police Department, and the VA health care controversy. (Starts at 48:00)
  • Massachusetts Treasurer Steve Grossman returned to Studio Three for a final pre-primary interview. (Starts at 1:11:02)
  • Jim and Margery opened the lines to ask listeners if they'd use the app Pager — a new service that puts you in direct contact with doctors, at all hours, at the push of a few buttons. (Starts at 1:34:11)