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Two days after the State of the Union address, President Obama will sit down for a round of unusual interviews. There's a good chance he'll get a question that none of his predecessors have ever had to answer.

One distinct possibility: "Mr. President, is you OK? Is you good? 'Cuz I wanted to know."

That's the signature greeting of GloZell Green, the self-dubbed "Queen of YouTube." Green is one of three YouTube sensations — the others are Bethany Mota and Hank Green — who will interview the president at the White House about the policies outlined in his speech. Viewers can follow along on the White House YouTube account, and ask questions via social media using the hashtag #YouTubeAsksObama.

The practice of bypassing traditional media outlets in favor of more unconventional forums is a familiar one for the Obama White House. Obama famously appeared on actor and comedian Zach Galifianakis' web-based parody talk show " Between Two Ferns" last year to plug government health care, primarily to young Americans.

The webisode has logged about 28 million views since it first launched on humor site Funny Or Die on March 11, 2014. The next day, healthcare.gov experienced a 40 percent bump in traffic, according to a message from the verified Twitter account for the website.

Here's a look at the three YouTube personalities who will be interviewing the president live on Thursday:

GloZell Green

Green is a California-based entertainer who shot to fame after posting comedy videos on YouTube, which soon went viral. A video of her coughing and sputtering after consuming a ladle full of cinnamon garnered more than 42 million views.

According to her online biography, GloZell has posted more than 2,000 videos online, has over 3 million subscribers to her YouTube channel and about 529 million total page views. She has leveraged her internet fame to appearances on television shows including the Dr. Oz Show and Showbiz Tonight, and secured a book deal.

Bethany Mota

Nineteen-year-old Mota has more than 8 million subscribers to her YouTube account, which features makeup tips, DIY projects and home decoration advice aimed at teen girls and young women. In a video discussing her favorite October beauty products, Mota mentions immediately putting up Christmas decorations after Halloween because she "...just decided that my room looked really sad."

In a January 2014 article, Business Insider reports that the fashion maven earned about half a million dollars through her videos, and had more Instagram followers than Vogue, Marie Claire, Elle, Glamour and Cosmopolitan magazines combined.

Hank Green

More than 2 million YouTubers subscribe to the vlogbrothers channel to watch Hank Green and his brother John Green, author of The Fault in our Stars, rant about Harry Potter, Hong Kong, net neutrality and farting. The project began when the brother realized they were only communicating through text messages and email, and decided to create video blogs for each other to stay in touch.

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