Dr. Guarente discusses his research, which focuses on issues surrounding aging. **Leonard P. Guarente** has written numerous papers and books, the latest of which, Ageless Quest, was published in 2003. He served as associate editor of Nucleic Acids Research from 1983-1988 and associate editor of Molecular and Cellular Biology from 1986-1988, 1989-1991. Dr. Guarente has also served on the editorial boards of Developmental Cell,Science magazine, SAGE KE, and Experimental Gerontology. He founded Elixir Pharmaceuticals in 2000. Dr. Guarente has received many awards and lectureships, including the Academy of the American Society for Health Aging Investigator of 2001, Novartis Professor of Biology, 2000, Ellison Medical Foundation Senior Scholar, 1999-2002, Ida Beam Distinguished Lecturer, 2001, Earle P. Charlton Lectureship, 1998, elected to the American Academy of Microbiology, 1998, Presidential Young Investigator Award from the National Science Foundation, 1984-1989 and the Thomas D. and Virginia W. Cabot Career Development Professorship, 1989-1992.